Endometrial claudin-4 and leukemia inhibitory factor are associated with assisted reproduction outcome
نویسندگان
چکیده
منابع مشابه
Endometrial claudin-4 and leukemia inhibitory factor are associated with assisted reproduction outcome
BACKGROUND Claudin-4 (CLDN4) is one of several proteins that act as molecular mediators of embryo implantation. Recently, we examined immunolabeling of leukemia inhibitory factor (LIF) in the endometrial tissue of 52 IVF patients, and found that LIF staining intensity was strongly correlated with successful pregnancy initiation. In the same set of patients, we have now examined endometrial CLDN...
متن کاملLeukemia Inhibitory Factor and Human Endometrial Receptivity
Embryo implantation requires both an activated blastocyst and a receptive endometrium. The human endometrium undergoes extensive remodeling in each menstrual cycle to prepare the endometrium for implantation, should conception occur in that cycle. For most of the cycle, the endometrium is retained in a non-receptive or refractory state and it will support implantation of the blastocyst for only...
متن کاملP-194: Investigation The Association of Leukemia Inhibitory Factor Gene Polymorphism with IVF Outcome in Infertile Women
Background: Clinical infertility is defined as the inability to become pregnant after 12 months of unprotected intercourse. Worldwide, more than 80 million couples suffer from infertility;the majority of this population are residents of developing countries. In vitro fertilization (IVF) is the most successful of the infertility treatments, and for many people is the last possibility for pregnan...
متن کاملAberrant expression of leukemia inhibitory factor receptor (LIFR) and leukemia inhibitory factor (LIF) is associated with tubal pregnancy occurrence.
BACKGROUND/AIM Tubal pregnancy is a major cause of maternal death in the first trimester and exploration of its underlying molecular mechanism is of great importance. This study aimed to explore the association of tubal pregnancy with leukemia inhibitory factor (LIF) and leukemia inhibitory factor receptor (LIFR) expression in oviduct tissues. MATERIALS AND METHODS Immunohistochemistry was pe...
متن کاملUterine myomata and outcome of assisted reproduction.
The aim of this work was to study the effect of uterine myomata on the implantation rate and outcome in in-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). Among 406 patients, 51 (12.6%) were found to have uterine corporeal myomata. Twelve patients were excluded from the study as they had large myomata, submucous myomata or intramural myomata encroaching on the cavity. The...
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ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2009
ISSN: 1477-7827
DOI: 10.1186/1477-7827-7-30